Lineage for d4jh0b2 (4jh0 B:509-766)

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1382311Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest
  4. 1382312Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families) (S)
    many members have left-handed crossover connection between strand 8 and additional strand 9
  5. 1383605Family c.69.1.24: DPP6 catalytic domain-like [82497] (2 proteins)
    N-terminal domain is a 8-bladed beta-propeller
    automatically mapped to Pfam PF00326
  6. 1383612Protein Dipeptidyl peptidase IV/CD26, C-terminal domain [82498] (2 species)
  7. 1383613Species Human (Homo sapiens) [TaxId:9606] [82499] (68 PDB entries)
    Uniprot P27487 39-776 ! Uniprot P27487 ! Uniprot P27487
  8. 1383719Domain d4jh0b2: 4jh0 B:509-766 [227728]
    Other proteins in same PDB: d4jh0a1, d4jh0b1
    automated match to d1nu6a2
    complexed with 1md

Details for d4jh0b2

PDB Entry: 4jh0 (more details), 2.35 Å

PDB Description: Crystal structure of dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) (DPP-IV-WT) complex with bms-767778 AKA 2-(3-(aminomethyl)-4-(2,4- dichlorophenyl)-2-methyl-5-oxo-5,7-dihydro-6h-pyrrolo[3,4- b]pyridin-6-yl)-n,n-dimethylacetamide
PDB Compounds: (B:) dipeptidyl peptidase 4

SCOPe Domain Sequences for d4jh0b2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4jh0b2 c.69.1.24 (B:509-766) Dipeptidyl peptidase IV/CD26, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
mpskkldfiilnetkfwyqmilpphfdkskkypllldvyagpcsqkadtvfrlnwatyla
steniivasfdgrgsgyqgdkimhainrrlgtfevedqieaarqfskmgfvdnkriaiwg
wsyggyvtsmvlgsgsgvfkcgiavapvsrweyydsvyterymglptpednldhyrnstv
msraenfkqveyllihgtaddnvhfqqsaqiskalvdvgvdfqamwytdedhgiasstah
qhiythmshfikqcfslp

SCOPe Domain Coordinates for d4jh0b2:

Click to download the PDB-style file with coordinates for d4jh0b2.
(The format of our PDB-style files is described here.)

Timeline for d4jh0b2:

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Domains from same chain:
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d4jh0b1