Lineage for d4gu6b_ (4gu6 B:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1930471Protein Focal adhesion kinase 1 (fak) [103292] (2 species)
    PTK group; FAK subfamily; non-membrane spanning protein tyrosine kinase
  7. 1930475Species Human (Homo sapiens) [TaxId:9606] [103293] (15 PDB entries)
  8. 1930481Domain d4gu6b_: 4gu6 B: [227710]
    automated match to d3pxka_
    complexed with 10n

Details for d4gu6b_

PDB Entry: 4gu6 (more details), 1.95 Å

PDB Description: focal adhesion kinase catalytic domain in complex with n-{3-[(5-cyano-2-phenyl-1h-pyrrolo[2,3-b]pyridin-4-ylamino)- methyl]-pyridin-2-yl}-n-methyl-methanesulfonamide
PDB Compounds: (B:) Focal adhesion kinase 1

SCOPe Domain Sequences for d4gu6b_:

Sequence, based on SEQRES records: (download)

>d4gu6b_ d.144.1.7 (B:) Focal adhesion kinase 1 (fak) {Human (Homo sapiens) [TaxId: 9606]}
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikwmapesi
nfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlysl
mtkcwaydpsrrprftelkaqlstileeekaq

Sequence, based on observed residues (ATOM records): (download)

>d4gu6b_ d.144.1.7 (B:) Focal adhesion kinase 1 (fak) {Human (Homo sapiens) [TaxId: 9606]}
yeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlstal
ayleskrfvhrdiaarnvlvssndcvklgdfglsrlpikwmapesinfrrftsasdvwmf
gvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrpr
ftelkaqlstileeekaq

SCOPe Domain Coordinates for d4gu6b_:

Click to download the PDB-style file with coordinates for d4gu6b_.
(The format of our PDB-style files is described here.)

Timeline for d4gu6b_: