SCOPe 2.08: Domain d4bjkd1: 4bjk D:32-478

Lineage for d4bjkd1 (4bjk D:32-478)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (99 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [194968] (9 PDB entries)

8. Domain d4bjkd1: 4bjk D:32-478 [227664]
   Other proteins in same PDB: d4bjka2, d4bjkb2, d4bjkc2, d4bjkd2
   automated match to d3khma_
   complexed with 18i, hem

Details for d4bjkd1

PDB Entry: 4bjk, 2.67 Å

PDB Description: CYP51 of Trypanosoma brucei bound to (S)-N-(3-(1H-indol-3-yl)-1-oxo-1- (pyridin-4-ylamino)propan-2-yl)-3,3'-difluoro-(1,1'-biphenyl)-4- carboxamide

PDB Compounds: (D:) lanosterol 14-alpha-demethylase

SCOPe Domain Sequences for d4bjkd1:

Sequence, based on SEQRES records:

>d4bjkd1 a.104.1.0 (D:32-478) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
ppmypvtvpilghiiqfgksplgfmqeckrqlksgiftinivgkrvtivgdphehsrffl
prnevlsprevysfmvpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhevr
kfmaanwdkdegeinlledcstmiintacqclfgedlrkrldarrfaqllakmesslipa
avflpillklplpqsarcheartelqkilseiiiarkaaavnkdsstsdllsgllsavyr
dgtpmslhevcgmivaamfagqhtssitttwsmlhlmhpanvkhlealrkeieefpaqln
ynnvmdempfaercaresirrdppllmlmrkvmadvkvgsyvvpkgdiiacspllshhde
eafpeprrwdperdekvegafigfgagvhkcigqkfgllqvktilatafrsydfqllrde
vpdpdyhtmvvgptasqcrvkyirrka

Sequence, based on observed residues (ATOM records):

>d4bjkd1 a.104.1.0 (D:32-478) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
ppmypvtvpilghiiqfgksplgfmqeckrqlksgiftinivgkrvtivgdphehsrffl
prnevlsprevysfmvpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqhevr
kfmaanwdkdegeinlledcstmiintacqclfgedlrkrldarrfaqllakmesslipa
avflpillklplpqsarcheartelqkilseiiiarkaastsdllsgllsavyrdgtpms
lhevcgmivaamfagqhtssitttwsmlhlmhpanvkhlealrkeieefpaqlnynnvmd
empfaercaresirrdppllmlmrkvmadvkvgsyvvpkgdiiacspllshhdeeafpep
rrwdperdekvegafigfgagvhkcigqkfgllqvktilatafrsydfqllrdevpdpdy
htmvvgptasqcrvkyirrka

Timeline for d4bjkd1:

• d4bjkd1 first appeared in SCOPe 2.03, called d4bjkd_
  
• d4bjkd1 appears in SCOPe 2.07