SCOPe 2.08: Domain d4b80a_: 4b80 A:

Lineage for d4b80a_ (4b80 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein automated matches [190065] (7 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [187006] (56 PDB entries)

8. Domain d4b80a_: 4b80 A: [227642]
   automated match to d2c0pa_
   complexed with a36, edo, nag, p4c, peg, pge, so4

Details for d4b80a_

PDB Entry: 4b80, 2.5 Å

PDB Description: mus musculus acetylcholinesterase in complex with n-(2-diethylamino- ethyl)-1-(4-fluoro-phenyl)-methanesulfonamide

PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d4b80a_:

Sequence, based on SEQRES records:

>d4b80a_ c.69.1.1 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
egredpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvl
dattfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiyg
ggfysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlal
qwvqeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvs
agearrratllarlvgcppggaggndteliaclrtrpaqdlvdhewhvlpqesifrfsfv
pvvdgdflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqfl
agvrigvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaa
qgarvyayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkyw
tnfartgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkll
sa

Sequence, based on observed residues (ATOM records):

>d4b80a_ c.69.1.1 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
egredpqllvrvrggqlrgirlkapggpvsaflgipfaeppvgsrrfmppepkrpwsgvl
dattfqnvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprpasptpvliwiyg
ggfysgaasldvydgrflaqvegavlvsmnyrvgtfgflalpgsreapgnvglldqrlal
qwvqeniaafggdpmsvtlfgesagaasvgmhilslpsrslfhravlqsgtpngpwatvs
agearrratllarlvgcpggndteliaclrtrpaqdlvdhewhvlpqesifrfsfvpvvd
gdflsdtpealintgdfqdlqvlvgvvkdegsyflvygvpgfskdneslisraqflagvr
igvpqasdlaaeavvlhytdwlhpedpthlrdamsavvgdhnvvcpvaqlagrlaaqgar
vyayifehrastltwplwmgvphgyeiefifglpldpslnytteerifaqrlmkywtnfa
rtgdpndprdskspqwppyttaaqqyvslnlkplevrrglraqtcafwnrflpkllsa

Timeline for d4b80a_:

• d4b80a_ first appeared in SCOPe 2.03
  
• d4b80a_ appears in SCOPe 2.07