SCOPe 2.06: Domain d4efka_: 4efk A:

Lineage for d4efka_ (4efk A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.4: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63976] (2 proteins)
   contains C-terminal subdomain similar to one structural repeat of the Creatinase/aminopeptidase family
   automatically mapped to Pfam PF02569

6. Protein Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63977] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [89615] (48 PDB entries)

8. Domain d4efka_: 4efk A: [227451]
   automated match to d1n2ga_
   complexed with 0oc, eoh, gol, imd, so4

Details for d4efka_

PDB Entry: 4efk, 1.7 Å

PDB Description: pantothenate synthetase in complex with n,n-dimethylthiophene-3-sulfonamide

PDB Compounds: (A:) Pantothenate synthetase

SCOPe Domain Sequences for d4efka_:

Sequence, based on SEQRES records:

>d4efka_ c.26.1.4 (A:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
pafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsvvv
vsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqpgpl
aaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvg
vptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaap
gvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieigtfag

Sequence, based on observed residues (ATOM records):

>d4efka_ c.26.1.4 (A:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
pafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsvvv
vsifvnpmqfayprtpdddlaqlraegveiaftpttaamypdglrttvqpgplaaelegg
prpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvgvptvrea
dglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaapgvavdyl
elrdiglgplngsgrllvaarlgttrlldniaieigtfag

Timeline for d4efka_:

• d4efka_ first appeared in SCOPe 2.03
  
• d4efka_ appears in SCOPe 2.05
  
• d4efka_ appears in SCOPe 2.07
  
• d4efka_ appears in the current release, SCOPe 2.08