SCOPe 2.06: Species: Trypanosoma brucei [TaxId: 5702]

Lineage for Species: Trypanosoma brucei [TaxId: 5702]

Root: SCOPe 2.06
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein Dihydropteridin reductase (pteridine reductase) [51769] (7 species)
Species Trypanosoma brucei [TaxId:5702] [226783] (15 PDB entries)

PDB entries in Species: Trypanosoma brucei [TaxId: 5702]:

Domain(s) for 3bmc:
1. Domain d3bmca_: 3bmc A: [208663]
  automated match to d1p33a_
  complexed with fol, nap
2. Domain d3bmcb_: 3bmc B: [208664]
  automated match to d1p33a_
  complexed with fol, nap
3. Domain d3bmcc_: 3bmc C: [208665]
  automated match to d1p33a_
  complexed with fol, nap
4. Domain d3bmcd_: 3bmc D: [208666]
  automated match to d1p33a_
  complexed with fol, nap
Domain(s) for 3bmn:
1. Domain d3bmna_: 3bmn A: [208667]
  automated match to d1p33a_
  complexed with act, ax3, edo, gol, nap
2. Domain d3bmnb_: 3bmn B: [208668]
  automated match to d1p33a_
  complexed with act, ax3, edo, gol, nap
3. Domain d3bmnc_: 3bmn C: [208669]
  automated match to d1p33a_
  complexed with act, ax3, edo, gol, nap
4. Domain d3bmnd_: 3bmn D: [208670]
  automated match to d1p33a_
  complexed with act, ax3, edo, gol, nap
Domain(s) for 3bmo:
1. Domain d3bmoa_: 3bmo A: [208671]
  automated match to d1p33a_
  complexed with act, ax4, d1d, dtt, gol, na, nap
2. Domain d3bmob_: 3bmo B: [208672]
  automated match to d1p33a_
  complexed with act, ax4, d1d, dtt, gol, na, nap
3. Domain d3bmoc_: 3bmo C: [208673]
  automated match to d1p33a_
  complexed with act, ax4, d1d, dtt, gol, na, nap
4. Domain d3bmod_: 3bmo D: [208674]
  automated match to d1p33a_
  complexed with act, ax4, d1d, dtt, gol, na, nap
Domain(s) for 3bmq:
1. Domain d3bmqa_: 3bmq A: [208675]
  automated match to d1p33a_
  complexed with act, ax5, dtt, gol, nap
2. Domain d3bmqb_: 3bmq B: [208676]
  automated match to d1p33a_
  complexed with act, ax5, dtt, gol, nap
3. Domain d3bmqc_: 3bmq C: [208677]
  automated match to d1p33a_
  complexed with act, ax5, dtt, gol, nap
4. Domain d3bmqd_: 3bmq D: [208678]
  automated match to d1p33a_
  complexed with act, ax5, dtt, gol, nap
Domain(s) for 3gn1:
1. Domain d3gn1a_: 3gn1 A: [210599]
  automated match to d1p33a_
  complexed with act, ax7, nap
2. Domain d3gn1b_: 3gn1 B: [210600]
  automated match to d1p33a_
  complexed with act, ax7, nap
3. Domain d3gn1c_: 3gn1 C: [210601]
  automated match to d1p33a_
  complexed with act, ax7, nap
4. Domain d3gn1d_: 3gn1 D: [210602]
  automated match to d1p33a_
  complexed with act, ax7, nap
Domain(s) for 3gn2:
1. Domain d3gn2a_: 3gn2 A: [210603]
  automated match to d1p33a_
  complexed with act, ax8, nap
2. Domain d3gn2b_: 3gn2 B: [210604]
  automated match to d1p33a_
  complexed with act, ax8, nap
3. Domain d3gn2c_: 3gn2 C: [210605]
  automated match to d1p33a_
  complexed with act, ax8, nap
4. Domain d3gn2d_: 3gn2 D: [210606]
  automated match to d1p33a_
  complexed with act, ax8, nap
Domain(s) for 3mcv:
1. Domain d3mcva_: 3mcv A: [213206]
  automated match to d1p33a_
  complexed with act, mcv, nap
2. Domain d3mcvb_: 3mcv B: [213207]
  automated match to d1p33a_
  complexed with act, mcv, nap
3. Domain d3mcvc_: 3mcv C: [213208]
  automated match to d1p33a_
  complexed with act, mcv, nap
4. Domain d3mcvd_: 3mcv D: [213209]
  automated match to d1p33a_
  complexed with act, mcv, nap
Domain(s) for 4wcd:
1. Domain d4wcda_: 4wcd A: [277601]
  automated match to d3bmob_
  complexed with 3kh, act, gol, nap
2. Domain d4wcdb_: 4wcd B: [277602]
  automated match to d3bmob_
  complexed with 3kh, act, gol, nap
3. Domain d4wcdc_: 4wcd C: [277600]
  automated match to d3bmob_
  complexed with 3kh, act, gol, nap
4. Domain d4wcdd_: 4wcd D: [277603]
  automated match to d3bmob_
  complexed with 3kh, act, gol, nap
Domain(s) for 4wcf:
1. Domain d4wcfa_: 4wcf A: [277330]
  automated match to d3bmob_
  complexed with 3kn, act, gol, nap
2. Domain d4wcfb_: 4wcf B: [277329]
  automated match to d3bmob_
  complexed with 3kn, act, gol, nap
3. Domain d4wcfc_: 4wcf C: [277328]
  automated match to d3bmob_
  complexed with 3kn, act, gol, nap
4. Domain d4wcfd_: 4wcf D: [277332]
  automated match to d3bmob_
  complexed with 3kn, act, gol, nap
Domain(s) for 5izc:
1. Domain d5izca_: 5izc A: [332653]
  automated match to d3bmob_
  complexed with 6f4, act, gol, nap
2. Domain d5izcb_: 5izc B: [332542]
  automated match to d3bmob_
  complexed with 6f4, act, gol, nap
3. Domain d5izcc_: 5izc C: [332605]
  automated match to d3bmob_
  complexed with 6f4, act, gol, nap
4. Domain d5izcd_: 5izc D: [332565]
  automated match to d3bmob_
  complexed with 6f4, act, gol, nap
Domain(s) for 5jcj:
1. Domain d5jcja_: 5jcj A: [321414]
  automated match to d3bmob_
  complexed with 6jm, act, nap
2. Domain d5jcjb_: 5jcj B: [321406]
  automated match to d3bmob_
  complexed with 6jm, act, nap
3. Domain d5jcjc_: 5jcj C: [321501]
  automated match to d3bmob_
  complexed with 6jm, act, nap
4. Domain d5jcjd_: 5jcj D: [321473]
  automated match to d3bmob_
  complexed with 6jm, act, nap
Domain(s) for 5jcx:
1. Domain d5jcxa_: 5jcx A: [321429]
  automated match to d3bmob_
  complexed with act, cc6, gol, nap
2. Domain d5jcxb_: 5jcx B: [321466]
  automated match to d3bmob_
  complexed with act, cc6, gol, nap
3. Domain d5jcxc_: 5jcx C: [321413]
  automated match to d3bmob_
  complexed with act, cc6, gol, nap
4. Domain d5jcxd_: 5jcx D: [321430]
  automated match to d3bmob_
  complexed with act, cc6, gol, nap
Domain(s) for 5jdc:
1. Domain d5jdca_: 5jdc A: [321388]
  automated match to d3bmob_
  complexed with 6jp, act, gol, nap
2. Domain d5jdcb_: 5jdc B: [321485]
  automated match to d3bmob_
  complexed with 6jp, act, gol, nap
3. Domain d5jdcc_: 5jdc C: [321389]
  automated match to d3bmob_
  complexed with 6jp, act, gol, nap
4. Domain d5jdcd_: 5jdc D: [321457]
  automated match to d3bmob_
  complexed with 6jp, act, gol, nap
Domain(s) for 5jdi:
1. Domain d5jdia_: 5jdi A: [321381]
  automated match to d3bmob_
  complexed with 6jo, act, nap
2. Domain d5jdib_: 5jdi B: [321420]
  automated match to d3bmob_
  complexed with 6jo, act, nap
3. Domain d5jdic_: 5jdi C: [321449]
  automated match to d3bmob_
  complexed with 6jo, act, nap
4. Domain d5jdid_: 5jdi D: [321450]
  automated match to d3bmob_
  complexed with 6jo, act, nap
Domain(s) for 5k6a:
1. Domain d5k6aa_: 5k6a A: [331674]
  automated match to d3bmob_
  complexed with 6qt, act, nap
2. Domain d5k6ab_: 5k6a B: [331660]
  automated match to d3bmob_
  complexed with 6qt, act, nap
3. Domain d5k6ac_: 5k6a C: [331682]
  automated match to d3bmob_
  complexed with 6qt, act, nap
4. Domain d5k6ad_: 5k6a D: [331771]
  automated match to d3bmob_
  complexed with 6qt, act, nap

More info for Species Trypanosoma brucei [TaxId:5702] from c.2.1.2 Dihydropteridin reductase (pteridine reductase)

Timeline for Species Trypanosoma brucei [TaxId:5702] from c.2.1.2 Dihydropteridin reductase (pteridine reductase):

Species Trypanosoma brucei [TaxId:5702] from c.2.1.2 Dihydropteridin reductase (pteridine reductase) first appeared in SCOPe 2.03
Species Trypanosoma brucei [TaxId:5702] from c.2.1.2 Dihydropteridin reductase (pteridine reductase) appears in SCOPe 2.05
Species Trypanosoma brucei [TaxId:5702] from c.2.1.2 Dihydropteridin reductase (pteridine reductase) appears in SCOPe 2.07
Species Trypanosoma brucei [TaxId:5702] from c.2.1.2 Dihydropteridin reductase (pteridine reductase) appears in the current release, SCOPe 2.08