SCOPe 2.04: Domain d4loud2: 4lou D:107-211

Lineage for d4loud2 (4lou D:107-211)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [88567] (346 PDB entries)
   Uniprot P01837# KAC_MOUSE Ig kappa chain C region; 99% sequence identity ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! Uniprot P01837 # KAC_MOUSE Ig kappa chain C region ! Uniprot P01837 # KAC_MOUSE (P01837) Ig kappa chain C region ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01837 # ! KAC_MOUSE Ig kappa chain C region

8. Domain d4loud2: 4lou D:107-211 [224738]
   Other proteins in same PDB: d4loua_, d4loub_, d4louc1, d4louc2, d4loud1, d4loue1, d4loue2, d4louf1
   automated match to d1otsd2
   mutant

Details for d4loud2

PDB Entry: 4lou, 2.98 Å

PDB Description: Structure of the E148Q mutant of CLC-ec1 deltaNC construct in the absence of halide

PDB Compounds: (D:) Fab light chain

SCOPe Domain Sequences for d4loud2:

Sequence; same for both SEQRES and ATOM records:

>d4loud2 b.1.1.2 (D:107-211) Immunoglobulin light chain kappa constant domain, CL-kappa {Mouse (Mus musculus) [TaxId: 10090]}
radaaptvsifppsseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqd
skdstysmsstltltkdeyerhnsytceathktstspivksfnra

Timeline for d4loud2:

• d4loud2 first appeared in SCOPe 2.03
  
• d4loud2 appears in SCOPe 2.05
  
• d4loud2 appears in the current release, SCOPe 2.08