SCOPe 2.08: Domain d4lkca1: 4lkc A:2-108

Lineage for d4lkca1 (4lkc A:2-108)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.0: automated matches [191470] (1 protein)
   not a true family

6. Protein automated matches [190740] (31 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187920] (1793 PDB entries)

8. Domain d4lkca1: 4lkc A:2-108 [224694]
   Other proteins in same PDB: d4lkca2, d4lkcb_
   automated match to d1rhha1

Details for d4lkca1

PDB Entry: 4lkc, 2.2 Å

PDB Description: An Antibody Against the C-terminal Domain of PCSK9 lowers LDL Cholesterol Levels in vivo

PDB Compounds: (A:) Fab fragment of PCSK9 antibody

SCOPe Domain Sequences for d4lkca1:

Sequence; same for both SEQRES and ATOM records:

>d4lkca1 b.1.1.0 (A:2-108) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aiqltqspsslsasvgdrvtitcrasqgissalawyqqkpgkapklliydasslesgvps
rfsgsgsgtdftltisslqpedfatyycqqfnsylitfgqgtrleik

Timeline for d4lkca1:

• d4lkca1 first appeared in SCOPe 2.03
  
• d4lkca1 appears in SCOPe 2.07