SCOPe 2.04: Domain d4lghb_: 4lgh B:

Lineage for d4lghb_ (4lgh B:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein c-src tyrosine kinase [56155] (2 species)
   PTK group; Src subfamily; non-membrane spanning protein tyrosine kinase

7. Species Chicken (Gallus gallus) [TaxId:9031] [56157] (35 PDB entries)

8. Domain d4lghb_: 4lgh B: [224665]
   automated match to d2z8ca1
   complexed with 0jn

Details for d4lghb_

PDB Entry: 4lgh, 2.84 Å

PDB Description: crystal structure of 1nm-pp1 bound to analog-sensitive src kinase

PDB Compounds: (B:) Proto-oncogene tyrosine-protein kinase Src

SCOPe Domain Sequences for d4lghb_:

Sequence, based on SEQRES records:

>d4lghb_ d.144.1.7 (B:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
aweipreslrlevklgqgcfgevwmgtwngttrvaiktlkpgtmspeaflqeaqvmkklr
heklvqlyavvseepiyivgeymskgslldflkgemgkylrlpqlvdmaaqiasgmayve
rmnyvhrdlraanilvgenlvckvadfglarliedneytarqgakfpikwtapeaalygr
ftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqc
wrkdpeerptfeylqafledyftstepqyqpgenl

Sequence, based on observed residues (ATOM records):

>d4lghb_ d.144.1.7 (B:) c-src tyrosine kinase {Chicken (Gallus gallus) [TaxId: 9031]}
aweipreslrlevklgqcfgevwmgtwngttrvaiktlkpeaqvmkklrheklvqlyavv
seepiyivgeymskgslldflkgemgkylrlpqlvdmaaqiasgmayvermnyvhrdlra
anilvgenlvckvadfglpikwtapeaalygrftiksdvwsfgilltelttkgrvpypgm
vnrevldqvergyrmpcppecpeslhdlmcqcwrkdpeerptfeylqafledyftstepq
yqpgenl

Timeline for d4lghb_:

• d4lghb_ first appeared in SCOPe 2.03
  
• d4lghb_ appears in SCOPe 2.05
  
• d4lghb_ appears in the current release, SCOPe 2.08