SCOP 1.73: Domain d1svcp2: 1svc P:43-250

Lineage for d1svcp2 (1svc P:43-250)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (7 families)

5. Family b.2.5.3: Rel/Dorsal transcription factors, DNA-binding domain [81315] (6 proteins)

6. Protein p50 subunit of NF-kappa B (NFKB), N-terminal domain [49423] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49424] (1 PDB entry)

8. Domain d1svcp2: 1svc P:43-250 [22443]
   Other proteins in same PDB: d1svcp1
   protein/DNA complex; mutant

Details for d1svcp2

PDB Entry: 1svc, 2.6 Å

PDB Description: nfkb p50 homodimer bound to dna

PDB Compounds: (P:) protein (nuclear factor kappa-b (nf-kb))

SCOP Domain Sequences for d1svcp2:

Sequence; same for both SEQRES and ATOM records:

>d1svcp2 b.2.5.3 (P:43-250) p50 subunit of NF-kappa B (NFKB), N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
pylqileqpkqrgfrfryvaegpshgglpgasseknkksypqvkicnyvgpakvivqlvt
ngknihlhahslvgkhcedgictvtagpkdmvvgfanlgilhvtkkkvfetlearmteac
irgynpgllvhpdlaylqaegggdrqlgdrekelirqaalqqtkemdlsvvrlmftaflp
dstgsftrrlepvvsdaiydskapnasn

Timeline for d1svcp2:

• d1svcp2 first appeared (with stable ids) in SCOP 1.55
  
• d1svcp2 appears in SCOP 1.71
  
• d1svcp2 appears in SCOP 1.75
  
• d1svcp2 appears in the current release, SCOPe 2.08