SCOPe 2.08: Domain d4kb7b_: 4kb7 B:

Lineage for d4kb7b_ (4kb7 B:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (9 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.4: RNA-dependent RNA-polymerase [56694] (3 proteins)

6. Protein Viral RNA polymerase [56695] (17 species)

7. Species Hepatitis C virus [TaxId:420174] [188905] (22 PDB entries)

8. Domain d4kb7b_: 4kb7 B: [224249]
   automated match to d4kbia_
   protein/RNA complex; complexed with 690

Details for d4kb7b_

PDB Entry: 4kb7, 1.85 Å

PDB Description: hcv ns5b gt1b n316y with cmpd 32

PDB Compounds: (B:) HCV Polymerase

SCOPe Domain Sequences for d4kb7b_:

Sequence, based on SEQRES records:

>d4kb7b_ e.8.1.4 (B:) Viral RNA polymerase {Hepatitis C virus [TaxId: 420174]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsagqrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskygygakdvrnlssravnhih
svwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydvvs
tlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiy
qccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkas
aacraaklqdctmlvygddlvvicesagtqedaaslrvfteamtrysappgdppqpeydl
elitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlw
armilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspg
einrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpip
aasrldlsgwfvagysggdiyh

Sequence, based on observed residues (ATOM records):

>d4kb7b_ e.8.1.4 (B:) Viral RNA polymerase {Hepatitis C virus [TaxId: 420174]}
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsagqrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskygygakdvrnlssravnhih
svwkdlledtvtpidttimaknevfcvqperkparlivfpdlgvrvcekmalydvvstlp
qvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqcc
dlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaac
raaklqdctmlvygddlvvicesagtqedaaslrvfteamtrysappgdppqpeydleli
tscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarm
ilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgein
rvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpifvag
ysggdiyh

Timeline for d4kb7b_:

• d4kb7b_ first appeared in SCOPe 2.03
  
• d4kb7b_ appears in SCOPe 2.07