Lineage for d4jt8a_ (4jt8 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2107255Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2107256Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2107620Family c.31.1.0: automated matches [191352] (1 protein)
    not a true family
  6. 2107621Protein automated matches [190312] (10 species)
    not a true protein
  7. 2107640Species Human (Homo sapiens) [TaxId:9606] [224883] (17 PDB entries)
  8. 2107651Domain d4jt8a_: 4jt8 A: [223989]
    automated match to d1j8fc_
    complexed with 1nr, zn

Details for d4jt8a_

PDB Entry: 4jt8 (more details), 2.26 Å

PDB Description: Crystal Structure of human SIRT3 with ELT inhibitor 28 [4-(4-{2-[(2,2-dimethylpropanoyl)amino]ethyl}piperidin-1-yl)thieno[3,2-d]pyrimidine-6-carboxamide[
PDB Compounds: (A:) NAD-dependent protein deacetylase sirtuin-3, mitochondrial

SCOPe Domain Sequences for d4jt8a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4jt8a_ c.31.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4jt8a_:

Click to download the PDB-style file with coordinates for d4jt8a_.
(The format of our PDB-style files is described here.)

Timeline for d4jt8a_: