SCOPe 2.08: Domain d4jlta1: 4jlt A:28-491

Lineage for d4jlta1 (4jlt A:28-491)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome p450 2b4 [101375] (1 species)

7. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [101376] (11 PDB entries)
   Uniprot P00178

8. Domain d4jlta1: 4jlt A:28-491 [223887]
   Other proteins in same PDB: d4jlta2
   automated match to d1suoa_
   complexed with 8pr, cm5, gol, hem, po4, so4

Details for d4jlta1

PDB Entry: 4jlt, 2.14 Å

PDB Description: Crystal structure of P450 2B4(H226Y) in complex with paroxetine

PDB Compounds: (A:) Cytochrome P450 2B4

SCOPe Domain Sequences for d4jlta1:

Sequence, based on SEQRES records:

>d4jlta1 a.104.1.1 (A:28-491) Mammalian cytochrome p450 2b4 {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdfgmgkrsveeriq
eearclveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfs
lissfssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidv
yllrmekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqke
ieqvigshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipknte
vfpvlssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelf
lffttilqnfsiaspvppedidltpresgvgnvppsyqirflar

Sequence, based on observed residues (ATOM records):

>d4jlta1 a.104.1.1 (A:28-491) Mammalian cytochrome p450 2b4 {Rabbit (Oryctolagus cuniculus) [TaxId: 9986]}
gklppgpsplpvlgnllqmdrkgllrsflrlrekygdvftvylgsrpvvvlcgtdairea
lvdqaeafsgrgkiavvdpifqgygvifangerwralrrfslatmrdrsveeriqeearc
lveelrkskgalldntllfhsitsniicsivfgkrfdykdpvflrlldlffqsfslissf
ssqvfelfsgflkyfpgthrqiyrnlqeintfigqsvekhratldpsnprdfidvyllrm
ekdksdpssefhhqnliltvlslffagtettsttlrygfllmlkyphvtervqkeieqvi
gshrppalddrakmpytdaviheiqrlgdlipfgvphtvtkdtqfrgyvipkntevfpvl
ssalhdpryfetpntfnpghfldangalkrnegfmpfslgkriclgegiartelflfftt
ilqnfsiaspvppedidltpsgvgnvppsyqirflar

Timeline for d4jlta1:

• d4jlta1 first appeared in SCOPe 2.03, called d4jlta_
  
• d4jlta1 appears in SCOPe 2.07