SCOPe 2.08: Domain d4jkfb_: 4jkf B:

Lineage for d4jkfb_ (4jkf B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (18 families)
   consists of one domain of this fold

5. Family c.55.3.14: Prp8 beta-finger domain-like [159638] (1 protein)
   automatically mapped to Pfam PF12134

6. Protein Pre-mRNA splicing factor 8, Prp8 / Spp42 [159639] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [159640] (13 PDB entries)
   Uniprot Q6P2Q9 1760-2016! Uniprot Q6P2Q9 1771-1989

8. Domain d4jkfb_: 4jkf B: [223869]
   automated match to d3enba1
   complexed with mg

Details for d4jkfb_

PDB Entry: 4jkf, 1.95 Å

PDB Description: Open and closed forms of T1791P+R1865A human PRP8 RNase H-like domain with bound Mg ion

PDB Compounds: (B:) Pre-mRNA-processing-splicing factor 8

SCOPe Domain Sequences for d4jkfb_:

Sequence, based on SEQRES records:

>d4jkfb_ c.55.3.14 (B:) Pre-mRNA splicing factor 8, Prp8 / Spp42 {Human (Homo sapiens) [TaxId: 9606]}
lfsnqiiwfvddtnvyrvpihktfegnlttkpingaififnprtgqlflkiihtsvwagq
krlgqlakwktaeevaalirslpveeqpkqiivtakgmldplevhlldfpnivikgselq
lpfqaclkvekfgdlilkatepqmvlfnlyddwlktissytafsrlililralhvnndra
kvilkpdkttitephhiwptltdeewikvevqlkdlila

Sequence, based on observed residues (ATOM records):

>d4jkfb_ c.55.3.14 (B:) Pre-mRNA splicing factor 8, Prp8 / Spp42 {Human (Homo sapiens) [TaxId: 9606]}
lfsnqiiwfvddtnvyrvpitkpingaififnprtgqlflkiihtsvwagqkrlgqlakw
ktaeevaalirslpveeqpkqiivtakgmldplevhlldfpnivikgselqlpfqaclkv
ekfgdlilkatepqmvlfnlyddwlktissytafsrlililralhvnndrakvilkpdkt
titephhiwptltdeewikvevqlkdlila

Timeline for d4jkfb_:

• d4jkfb_ first appeared in SCOPe 2.03
  
• d4jkfb_ appears in SCOPe 2.07