Lineage for d4j7da_ (4j7d A:)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2712363Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 2712364Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 2712365Family a.42.1.1: SWIB/MDM2 domain [47593] (5 proteins)
    Pfam PF02201
  6. 2712372Protein MDM2 [47594] (2 species)
  7. 2712373Species African clawed frog (Xenopus laevis) [TaxId:8355] [47595] (12 PDB entries)
    Uniprot P56273 13-119
  8. 2712375Domain d4j7da_: 4j7d A: [223617]
    automated match to d1ycqa_
    complexed with i31, so4

Details for d4j7da_

PDB Entry: 4j7d (more details), 1.25 Å

PDB Description: The 1.25A crystal structure of humanized Xenopus MDM2 with a nutlin fragment, RO5045331
PDB Compounds: (A:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d4j7da_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4j7da_ a.42.1.1 (A:) MDM2 {African clawed frog (Xenopus laevis) [TaxId: 8355]}
meklvqptplllsllksagaqketftmkevlyhlgqyimakqlydekqqhivhcsndplg
elfgvqefsvkehrriyamisrnlvs

SCOPe Domain Coordinates for d4j7da_:

Click to download the PDB-style file with coordinates for d4j7da_.
(The format of our PDB-style files is described here.)

Timeline for d4j7da_: