Lineage for d4j3ea_ (4j3e A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1996222Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 1996223Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 1996224Family a.42.1.1: SWIB/MDM2 domain [47593] (5 protein domains)
    Pfam PF02201
  6. 1996231Protein MDM2 [47594] (2 species)
  7. 1996232Species African clawed frog (Xenopus laevis) [TaxId:8355] [47595] (12 PDB entries)
    Uniprot P56273 13-119
  8. 1996239Domain d4j3ea_: 4j3e A: [223536]
    automated match to d1ycqa_
    complexed with nut, so4

Details for d4j3ea_

PDB Entry: 4j3e (more details), 1.91 Å

PDB Description: The 1.9A crystal structure of humanized Xenopus Mdm2 with nutlin-3a
PDB Compounds: (A:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d4j3ea_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4j3ea_ a.42.1.1 (A:) MDM2 {African clawed frog (Xenopus laevis) [TaxId: 8355]}

SCOPe Domain Coordinates for d4j3ea_:

Click to download the PDB-style file with coordinates for d4j3ea_.
(The format of our PDB-style files is described here.)

Timeline for d4j3ea_: