SCOPe 2.08: Domain d4iwva2: 4iwv A:219-459

Lineage for d4iwva2 (4iwv A:219-459)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.1: Actin-like ATPase domain [53067] (16 families)
   duplication contains two domains of this fold

5. Family c.55.1.0: automated matches [227137] (1 protein)
   not a true family

6. Protein automated matches [226839] (64 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [224896] (72 PDB entries)

8. Domain d4iwva2: 4iwv A:219-459 [223455]
   Other proteins in same PDB: d4iwva3
   automated match to d1bdga2
   complexed with 1j9, glc, na

Details for d4iwva2

PDB Entry: 4iwv, 2.1 Å

PDB Description: crystals structure of human glucokinase in complex with small molecule activator

PDB Compounds: (A:) Glucokinase isoform 3

SCOPe Domain Sequences for d4iwva2:

Sequence, based on SEQRES records:

>d4iwva2 c.55.1.0 (A:219-459) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qcevgmivgtgcnacymeemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvd
essanpgqqlyekliggkymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqv
esdtgdrkqiynilstlglrpsttdcdivrracesvstraahmcsaglagvinrmresrs
edvmritvgvdgsvyklhpsfkerfhasvrrltpsceitfieseegsgrgaalvsavack
k

Sequence, based on observed residues (ATOM records):

>d4iwva2 c.55.1.0 (A:219-459) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qcevgmivgtgcnacymeemqnvelvegdegrmcvntewgafgdsgeldeflleydrlvd
essanpgqqlyekliggkymgelvrlvllrlvdenllfhgeaseqlrtrgafetrfvsqv
esgdrkqiynilstlglrpsttdcdivrracesvstraahmcsaglagvinrmresrsed
vmritvgvdgsvyklhpsfkerfhasvrrltpsceitfieseegsgrgaalvsavackk

Timeline for d4iwva2:

• d4iwva2 first appeared in SCOPe 2.03
  
• d4iwva2 appears in SCOPe 2.07