Lineage for d4isfa2 (4isf A:219-465)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2122050Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 2122051Superfamily c.55.1: Actin-like ATPase domain [53067] (16 families) (S)
    duplication contains two domains of this fold
  5. 2123183Family c.55.1.0: automated matches [227137] (1 protein)
    not a true family
  6. 2123184Protein automated matches [226839] (50 species)
    not a true protein
  7. 2123310Species Human (Homo sapiens) [TaxId:9606] [224896] (56 PDB entries)
  8. 2123338Domain d4isfa2: 4isf A:219-465 [223341]
    Other proteins in same PDB: d4isfa3
    automated match to d1bdga2
    complexed with 1fx, glc, iod

Details for d4isfa2

PDB Entry: 4isf (more details), 2.09 Å

PDB Description: Human glucokinase in complex with novel activator (2S)-3-cyclohexyl-2-(6-fluoro-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)-N-(1,3-thiazol-2-yl)propanamide
PDB Compounds: (A:) Glucokinase

SCOPe Domain Sequences for d4isfa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4isfa2 c.55.1.0 (A:219-465) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4isfa2:

Click to download the PDB-style file with coordinates for d4isfa2.
(The format of our PDB-style files is described here.)

Timeline for d4isfa2: