SCOPe 2.08: Domain d4ig8a1: 4ig8 A:3-201

Lineage for d4ig8a1 (4ig8 A:3-201)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.6: 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain [102937] (1 protein)
   similar overall structure to the first two domains of poly(A) polymerase, PAP

6. Protein 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain [102938] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [254760] (1 PDB entry)

8. Domain d4ig8a1: 4ig8 A:3-201 [223162]
   Other proteins in same PDB: d4ig8a2
   automated match to d1px5a2
   protein/RNA complex; complexed with dtp, mg

Details for d4ig8a1

PDB Entry: 4ig8, 2.7 Å

PDB Description: Structural basis for cytosolic double-stranded RNA surveillance by human OAS1

PDB Compounds: (A:) 2'-5'-oligoadenylate synthase 1

SCOPe Domain Sequences for d4ig8a1:

Sequence, based on SEQRES records:

>d4ig8a1 d.218.1.6 (A:3-201) 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
dlrntpaksldkfiedyllpdtcfrmqinhaidiicgflkercfrgssypvcvskvvkgg
ssgkgttlrgrsdadlvvflsplttfqdqlnrrgefiqeirrqleacqrerafsvkfevq
aprwgnpralsfvlsslqlgegvefdvlpafdalgqltggykpnpqiyvklieectdlqk
egefstcftelqrdflkqr

Sequence, based on observed residues (ATOM records):

>d4ig8a1 d.218.1.6 (A:3-201) 2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
dlrntpaksldkfiedyllpdtcfrmqinhaidiicgflkercfrgssypvcvskvvkgg
ssgkgttlrgrsdadlvvflsplttfqdqlnrrgefiqeirrqleacqrerafsvkfegn
pralsfvlsslqlgegvefdvlpafdalgqltggykpnpqiyvklieectdlqkegefst
cftelqrdflkqr

Timeline for d4ig8a1:

• d4ig8a1 first appeared in SCOPe 2.03
  
• d4ig8a1 appears in SCOPe 2.07