SCOPe 2.03: Domain d4i5na_: 4i5n A:

Lineage for d4i5na_ (4i5n A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.118: alpha-alpha superhelix [48370] (24 superfamilies)
   multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

4. Superfamily a.118.1: ARM repeat [48371] (24 families)

5. Family a.118.1.2: HEAT repeat [48385] (2 proteins)
   Pfam PF02985
   this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain

6. Protein Constant regulatory domain of protein phosphatase 2a, pr65alpha [48386] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48387] (12 PDB entries)

8. Domain d4i5na_: 4i5n A: [222944]
   Other proteins in same PDB: d4i5nc_, d4i5nf_
   automated match to d4i5la_
   complexed with ca, mn

Details for d4i5na_

PDB Entry: 4i5n, 2.8 Å

PDB Description: structural mechanism of trimeric pp2a holoenzyme involving pr70: insight for cdc6 dephosphorylation

PDB Compounds: (A:) Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

SCOPe Domain Sequences for d4i5na_:

Sequence; same for both SEQRES and ATOM records:

>d4i5na_ a.118.1.2 (A:) Constant regulatory domain of protein phosphatase 2a, pr65alpha {Human (Homo sapiens) [TaxId: 9606]}
mslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevll
alaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleah
fvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaas
klgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmpt
lrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvk
efcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllp
lflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieym
pllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvl
amsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqki
gpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

Timeline for d4i5na_:

• d4i5na_ is new in SCOPe 2.03-stable
  
• d4i5na_ appears in SCOPe 2.04
  
• d4i5na_ appears in the current release, SCOPe 2.08, called d4i5na1