Lineage for d4hz5c_ (4hz5 C:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1429695Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 1429696Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 1430131Family d.122.1.0: automated matches [227160] (1 protein)
    not a true family
  6. 1430132Protein automated matches [226867] (10 species)
    not a true protein
  7. 1430133Species Enterococcus faecalis [TaxId:226185] [226590] (9 PDB entries)
  8. 1430144Domain d4hz5c_: 4hz5 C: [222806]
    automated match to d1kzna_
    complexed with 19y

Details for d4hz5c_

PDB Entry: 4hz5 (more details), 2.7 Å

PDB Description: Pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity
PDB Compounds: (C:) DNA topoisomerase IV, B subunit

SCOPe Domain Sequences for d4hz5c_:

Sequence, based on SEQRES records: (download)

>d4hz5c_ d.122.1.0 (C:) automated matches {Enterococcus faecalis [TaxId: 226185]}
gleavrkrpgmyigstdsrglhhlvyeivdnavdealsgygneinvtiqkdnsicvadsg
rgmptgmhasgiptveviftvlhaggkfgqggyktsgglhgvgasvvnalskwlevhivr
dgveymerfedggkpvgtlkkigktkkrngtsvtflpddtifsttnfsyeilaerlresa
fllkgvkitltdergeepkeevfhyee

Sequence, based on observed residues (ATOM records): (download)

>d4hz5c_ d.122.1.0 (C:) automated matches {Enterococcus faecalis [TaxId: 226185]}
gleavrkrpgmyigstdsrglhhlvyeivdnavdealsgygneinvtiqkdnsicvadsg
rgmptgmhasgiptveviftvlhhgvgasvvnalskwlevhivrdgveymerfedggkpv
gtlkkigktkkrngtsvtflpddtifsttnfsyeilaerlresafllkgvkitltderge
epkeevfhyee

SCOPe Domain Coordinates for d4hz5c_:

Click to download the PDB-style file with coordinates for d4hz5c_.
(The format of our PDB-style files is described here.)

Timeline for d4hz5c_: