SCOPe 2.03: Domain d4hy1a2: 4hy1 A:216-377

Lineage for d4hy1a2 (4hy1 A:216-377)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.14: Ribosomal protein S5 domain 2-like [54210] (1 superfamily)
   core: beta(3)-alpha-beta-alpha; 2 layers: alpha/beta; left-handed crossover

4. Superfamily d.14.1: Ribosomal protein S5 domain 2-like [54211] (13 families)

5. Family d.14.1.0: automated matches [191504] (1 protein)
   not a true family

6. Protein automated matches [190826] (13 species)
   not a true protein

7. Species Francisella tularensis [TaxId:376619] [226592] (4 PDB entries)

8. Domain d4hy1a2: 4hy1 A:216-377 [222788]
   Other proteins in same PDB: d4hy1a1, d4hy1b1
   automated match to d1s16a1
   complexed with 19x

Details for d4hy1a2

PDB Entry: 4hy1, 1.9 Å

PDB Description: pyrrolopyrimidine inhibitors of dna gyrase b and topoisomerase iv, part i: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.

PDB Compounds: (A:) Topoisomerase IV, subunit B

SCOPe Domain Sequences for d4hy1a2:

Sequence, based on SEQRES records:

>d4hy1a2 d.14.1.0 (A:216-377) automated matches {Francisella tularensis [TaxId: 376619]}
tglkgyldhkleaetlpaepfiidnfsngdsyldavfcwcedpsesiknsyvnliptpqd
gthvtglkngiydaikayieknslsvknikitandsfaqlnyvisvkitnpqfagqtkek
lsnkdvtnfvatavkdlltiwlnqnpdearqiveniskvaqk

Sequence, based on observed residues (ATOM records):

>d4hy1a2 d.14.1.0 (A:216-377) automated matches {Francisella tularensis [TaxId: 376619]}
tglkgyldhkleaetlpaepfiidnfsngdsyldavfcwcedpsesiknsyvnliptpqd
gthvtglkngiydaikayieknsikitandsfaqlnyvisvkitnpqfagqtkeklsnkd
vtnfvatavkdlltiwlnqnpdearqiveniskvaqk

Timeline for d4hy1a2:

• d4hy1a2 is new in SCOPe 2.03-stable
  
• d4hy1a2 appears in SCOPe 2.04
  
• d4hy1a2 appears in the current release, SCOPe 2.08