SCOPe 2.08: Domain d4hxoa1: 4hxo A:44-167

Lineage for d4hxoa1 (4hxo A:44-167)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1052 PDB entries)

8. Domain d4hxoa1: 4hxo A:44-167 [222777]
   Other proteins in same PDB: d4hxoa2
   automated match to d2nxba_
   complexed with 1a6

Details for d4hxoa1

PDB Entry: 4hxo, 1.76 Å

PDB Description: brd4 bromodomain 1 complex with 3-{[(3-methyl-1,2-oxazol-5-yl) methyl]sulfanyl}[1,2,4]triazolo[4,3-a]pyridine inhibitor

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4hxoa1:

Sequence; same for both SEQRES and ATOM records:

>d4hxoa1 a.29.2.0 (A:44-167) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lpte

Timeline for d4hxoa1:

• d4hxoa1 first appeared in SCOPe 2.03, called d4hxoa_
  
• d4hxoa1 appears in SCOPe 2.07