SCOPe 2.08: Domain d4hxma1: 4hxm A:44-166

Lineage for d4hxma1 (4hxm A:44-166)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (15 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1052 PDB entries)

8. Domain d4hxma1: 4hxm A:44-166 [222775]
   Other proteins in same PDB: d4hxma2
   automated match to d3uvya_
   complexed with 1a8

Details for d4hxma1

PDB Entry: 4hxm, 1.5 Å

PDB Description: brd4 bromodomain 1 complex with n-{3-(2-oxo-2,3-dihydro-1,3-thiazol-4-yl)-5-[(thiophen-2-ylsulfonyl)amino]phenyl}butanamide inhibitor

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4hxma1:

Sequence; same for both SEQRES and ATOM records:

>d4hxma1 a.29.2.0 (A:44-166) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lpt

Timeline for d4hxma1:

• d4hxma1 first appeared in SCOPe 2.03, called d4hxma_
  
• d4hxma1 appears in SCOPe 2.07