Lineage for d4hcob2 (4hco B:505-594)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1945423Fold d.223: Polo-box domain [82614] (1 superfamily)
    beta(6)-alpha; antiparallel beta-sheet, meander
  4. 1945424Superfamily d.223.1: Polo-box domain [82615] (2 families) (S)
    Serine/threonine protein kinase-associated motif embedded in two distinct folds
  5. 1945433Family d.223.1.2: Polo-box duplicated region [102856] (1 protein)
    duplication: consists of two polo-box domains; binds phosphothreonine peptide
  6. 1945434Protein Serine/threonine-protein kinase plk C-terminal domain [102857] (2 species)
  7. 1945435Species Human (Homo sapiens) [TaxId:9606] [102858] (17 PDB entries)
  8. 1945483Domain d4hcob2: 4hco B:505-594 [222510]
    automated match to d1q4kb2
    complexed with gol, imw

Details for d4hcob2

PDB Entry: 4hco (more details), 2.75 Å

PDB Description: Human Plk1-PBD in complex with Thymoquinone at the phophopeptide binding site
PDB Compounds: (B:) Serine/threonine-protein kinase PLK1

SCOPe Domain Sequences for d4hcob2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4hcob2 d.223.1.2 (B:505-594) Serine/threonine-protein kinase plk C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
larlpylrtwfrtrsaiilhlsngsvqinffqdhtklilcplmaavtyidekrdfrtyrl
slleeygcckelasrlryartmvdkllssr

SCOPe Domain Coordinates for d4hcob2:

Click to download the PDB-style file with coordinates for d4hcob2.
(The format of our PDB-style files is described here.)

Timeline for d4hcob2:

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Domains from same chain:
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d4hcob1