SCOPe 2.06: Domain d4haia2: 4hai A:228-548

Lineage for d4haia2 (4hai A:228-548)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (42 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.11: Epoxide hydrolase [53525] (3 proteins)

6. Protein Mammalian epoxide hydrolase, C-terminal domain [53526] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102626] (40 PDB entries)

8. Domain d4haia2: 4hai A:228-548 [222454]
   Other proteins in same PDB: d4haia1
   automated match to d1vj5a2
   complexed with i23, mg, po4

Details for d4haia2

PDB Entry: 4hai, 2.55 Å

PDB Description: Crystal structure of human soluble epoxide hydrolase complexed with N-cycloheptyl-1-(mesitylsulfonyl)piperidine-4-carboxamide.

PDB Compounds: (A:) Bifunctional epoxide hydrolase 2

SCOPe Domain Sequences for d4haia2:

Sequence; same for both SEQRES and ATOM records:

>d4haia2 c.69.1.11 (A:228-548) Mammalian epoxide hydrolase, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
lptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyr
vlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalf
ypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfks
lfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyr
nmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtq
mdkptevnqilikwldsdarn

Timeline for d4haia2:

• d4haia2 first appeared in SCOPe 2.03
  
• d4haia2 appears in SCOPe 2.05
  
• d4haia2 appears in SCOPe 2.07
  
• d4haia2 appears in the current release, SCOPe 2.08