SCOPe 2.05: Domain d4h5xa1: 4h5x A:372-500

Lineage for d4h5xa1 (4h5x A:372-500)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.223: Polo-box domain [82614] (1 superfamily)
   beta(6)-alpha; antiparallel beta-sheet, meander

4. Superfamily d.223.1: Polo-box domain [82615] (2 families)
   Serine/threonine protein kinase-associated motif embedded in two distinct folds

5. Family d.223.1.2: Polo-box duplicated region [102856] (1 protein)
   duplication: consists of two polo-box domains; binds phosphothreonine peptide

6. Protein Serine/threonine-protein kinase plk C-terminal domain [102857] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102858] (17 PDB entries)

8. Domain d4h5xa1: 4h5x A:372-500 [222394]
   automated match to d3bzia1
   complexed with gol

Details for d4h5xa1

PDB Entry: 4h5x, 1.95 Å

PDB Description: human Plk1-PBD with a glycerol bound at the phophopeptide binding site

PDB Compounds: (A:) Serine/threonine-protein kinase PLK1

SCOPe Domain Sequences for d4h5xa1:

Sequence; same for both SEQRES and ATOM records:

>d4h5xa1 d.223.1.2 (A:372-500) Serine/threonine-protein kinase plk C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
chlsdmlqqlhsvnaskpserglvrqeeaedpacipifwvskwvdysdkyglgyqlcdns
vgvlfndstrlilyndgdslqyierdgtesyltvsshpnslmkkitllkyfrnymsehll
kaganitpr

Timeline for d4h5xa1:

• d4h5xa1 first appeared in SCOPe 2.03
  
• d4h5xa1 appears in SCOPe 2.04
  
• d4h5xa1 appears in SCOPe 2.06
  
• d4h5xa1 appears in the current release, SCOPe 2.08