Lineage for d4h4oa2 (4h4o A:430-548)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2122050Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 2123751Superfamily c.55.3: Ribonuclease H-like [53098] (15 families) (S)
    consists of one domain of this fold
  5. 2124881Family c.55.3.0: automated matches [191357] (1 protein)
    not a true family
  6. 2124882Protein automated matches [190396] (34 species)
    not a true protein
  7. 2124989Species Human immunodeficiency virus type 1 bh10 [TaxId:11678] [225195] (20 PDB entries)
  8. 2124994Domain d4h4oa2: 4h4o A:430-548 [222385]
    Other proteins in same PDB: d4h4oa1, d4h4oa3, d4h4ob_
    automated match to d1bqna1
    complexed with 506

Details for d4h4oa2

PDB Entry: 4h4o (more details), 2.9 Å

PDB Description: crystal structure of hiv-1 reverse transcriptase (rt) in complex with (e)-3-(3-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)ethoxy)- 4- fluorophenoxy)-5-fluorophenyl)acrylonitrile (jlj506), a non- nucleoside inhibitor
PDB Compounds: (A:) Reverse transcriptase/ribonuclease H, Exoribonuclease H, p66 RT

SCOPe Domain Sequences for d4h4oa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4h4oa2 c.55.3.0 (A:430-548) automated matches {Human immunodeficiency virus type 1 bh10 [TaxId: 11678]}

SCOPe Domain Coordinates for d4h4oa2:

Click to download the PDB-style file with coordinates for d4h4oa2.
(The format of our PDB-style files is described here.)

Timeline for d4h4oa2:

View in 3D
Domains from other chains:
(mouse over for more information)