SCOPe 2.07: Domain d4gzla_: 4gzl A:

Lineage for d4gzla_ (4gzl A:)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (80 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein Rac [52595] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [52596] (28 PDB entries)

8. Domain d4gzla_: 4gzl A: [222278]
   automated match to d2wm9b_
   complexed with gnp, ipa, mg; mutant

Details for d4gzla_

PDB Entry: 4gzl, 2 Å

PDB Description: Crystal structure of RAC1 Q61L mutant

PDB Compounds: (A:) ras-related c3 botulinum toxin substrate 1

SCOPe Domain Sequences for d4gzla_:

Sequence, based on SEQRES records:

>d4gzla_ c.37.1.8 (A:) Rac {Human (Homo sapiens) [TaxId: 9606]}
aikcvvvgdgavgktcllisyttnafpgeyiptvfdnysanvmvdgkpvnlglwdtagle
dydrlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrdd
kdtieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl

Sequence, based on observed residues (ATOM records):

>d4gzla_ c.37.1.8 (A:) Rac {Human (Homo sapiens) [TaxId: 9606]}
aikcvvvgdgavgktcllisyttnafpgyiptvfdnysanvmvdkpvnlglwdtagledy
drlrplsypqtdvflicfslvspasfenvrakwypevrhhcpntpiilvgtkldlrddkd
tieklkekkltpitypqglamakeigavkylecsaltqrglktvfdeairavl

Timeline for d4gzla_:

• d4gzla_ first appeared in SCOPe 2.03
  
• d4gzla_ appears in SCOPe 2.06