SCOPe 2.03: Domain d4gvja_: 4gvj A:

Lineage for d4gvja_ (4gvj A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d4gvja_: 4gvj A: [222208]
   automated match to d2qoha_
   complexed with adp, mg

Details for d4gvja_

PDB Entry: 4gvj, 2.03 Å

PDB Description: tyk2 (jh1) in complex with adenosine di-phosphate

PDB Compounds: (A:) Non-receptor tyrosine-protein kinase TYK2

SCOPe Domain Sequences for d4gvja_:

Sequence; same for both SEQRES and ATOM records:

>d4gvja_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptvfhkrylkkirdlgeghfgkvslycydptndgtgemvavkalkadagpqhrsgwkqei
dilrtlyhehiikykgccedagaaslqlvmeyvplgslrdylprhsiglaqlllfaqqic
egmaylhaqhyihrdlaarnvlldndrlvkigdfglakavpegheyyrvredgdspvfwy
apeclkeykfyyasdvwsfgvtlyellthcdssqspptkfleligiaqgqmtvlrltell
ergerlprpdkcpaevyhlmkncweteasfrptfenlipilktvhekyrh

Timeline for d4gvja_:

• d4gvja_ is new in SCOPe 2.03-stable
  
• d4gvja_ appears in SCOPe 2.04
  
• d4gvja_ appears in the current release, SCOPe 2.08, called d4gvja1