SCOPe 2.07: Domain d4grba_: 4grb A:

Lineage for d4grba_ (4grb A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Protein kinase CK2, alpha subunit [56142] (3 species)
   CMGC group; CK2 subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [75559] (180 PDB entries)

8. Domain d4grba_: 4grb A: [222099]
   automated match to d3ngaa_
   complexed with 0xg, cl

Details for d4grba_

PDB Entry: 4grb, 2.15 Å

PDB Description: Casein kinase 2 (CK2) bound to inhibitor

PDB Compounds: (A:) Casein kinase II subunit alpha

SCOPe Domain Sequences for d4grba_:

Sequence; same for both SEQRES and ATOM records:

>d4grba_ d.144.1.7 (A:) Protein kinase CK2, alpha subunit {Human (Homo sapiens) [TaxId: 9606]}
sgpvpsrarvytdvnthrpreywdyeshvvewgnqddyqlvrklgrgkysevfeainitn
nekvvvkilkpvkkkkikreikilenlrggpniitladivkdpvsrtpalvfehvnntdf
kqlyqtltdydirfymyeilkaldychsmgimhrdvkphnvmidhehrklrlidwglaef
yhpgqeynvrvasryfkgpellvdyqmydysldmwslgcmlasmifrkepffhghdnydq
lvriakvlgtedlydyidkynieldprfndilgrhsrkrwerfvhsenqhlvspealdfl
dkllrydhqsrltareamehpyfytvv

Timeline for d4grba_:

• d4grba_ first appeared in SCOPe 2.03
  
• d4grba_ appears in SCOPe 2.06
  
• d4grba_ appears in the current release, SCOPe 2.08