SCOPe 2.05: Domain d4gjda_: 4gjd A:

Lineage for d4gjda_ (4gjd A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.2: Pepsin-like [50646] (11 proteins)
   duplication: consists of two similar barrel domains
   N-terminal: barrel, partly opened; n*=6, S*=10

6. Protein Chymosin (synonym: renin) [50667] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50669] (66 PDB entries)

8. Domain d4gjda_: 4gjd A: [221953]
   automated match to d2v0zc_
   complexed with 0n0, nag, so4

Details for d4gjda_

PDB Entry: 4gjd, 2.65 Å

PDB Description: crystal structure of renin in complex with nvp-bgq311 (compound 12)

PDB Compounds: (A:) renin

SCOPe Domain Sequences for d4gjda_:

Sequence, based on SEQRES records:

>d4gjda_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
tlgnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyh
klfdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfml
aefdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdsensqslggqivlggs
dpqhyegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssiek
lmealgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaih
amdippptgptwalgatfirkfytefdrrnnrigfalar

Sequence, based on observed residues (ATOM records):

>d4gjda_ b.50.1.2 (A:) Chymosin (synonym: renin) {Human (Homo sapiens) [TaxId: 9606]}
tlgnttssviltnymdtqyygeigigtppqtfkvvfdtgssnvwvpsskcsrlytacvyh
klfdasdsssykhngteltlrystgtvsgflsqdiitvggitvtqmfgevtempalpfml
aefdgvvgmgfieqaigrvtpifdniisqgvlkedvfsfyynrdqslggqivlggsdpqh
yegnfhyinliktgvwqiqmkgvsvgsstllcedgclalvdtgasyisgstssieklmea
lgakkrlfdyvvkcnegptlpdisfhlggkeytltsadyvfqesysskklctlaihamdi
ppptgptwalgatfirkfytefdrrnnrigfalar

Timeline for d4gjda_:

• d4gjda_ first appeared in SCOPe 2.03
  
• d4gjda_ appears in SCOPe 2.04
  
• d4gjda_ appears in SCOPe 2.06
  
• d4gjda_ appears in the current release, SCOPe 2.08