SCOPe 2.08: Domain d4gg7a_: 4gg7 A:

Lineage for d4gg7a_ (4gg7 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4gg7a_: 4gg7 A: [221892]
   automated match to d3dkga_
   complexed with 0j8

Details for d4gg7a_

PDB Entry: 4gg7, 2.27 Å

PDB Description: Crystal structure of cMET in complex with novel inhibitor

PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d4gg7a_:

Sequence, based on SEQRES records:

>d4gg7a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnritdigevsq
fltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdlig
fglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyysvhnktga
klpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrll
qpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstf

Sequence, based on observed residues (ATOM records):

>d4gg7a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavkslnrigevsqflt
egiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirnethnptvkdligfgl
qvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkeyysvhnktgaklp
vkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpe
ycpdplyevmlkcwhpkaemrpsfselvsrisaifstf

Timeline for d4gg7a_:

• d4gg7a_ first appeared in SCOPe 2.03
  
• d4gg7a_ appears in SCOPe 2.07