SCOPe 2.06: Domain d4g7gc_: 4g7g C:

Lineage for d4g7gc_ (4g7g C:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.0: automated matches [191509] (1 protein)
   not a true family

6. Protein automated matches [190847] (64 species)
   not a true protein

7. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [194968] (7 PDB entries)

8. Domain d4g7gc_: 4g7g C: [221746]
   automated match to d3khma_
   complexed with hem, vfv

Details for d4g7gc_

PDB Entry: 4g7g, 2.05 Å

PDB Description: sterol 14-alpha demethylase (cyp51) from trypanosoma brucei in complex with the vni derivative (r)-n-(1-(3,4'-difluorobiphenyl-4-yl)-2-(1h- imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide [vni/vnf (vfv)]

PDB Compounds: (C:) Sterol 14-alpha-demethylase

SCOPe Domain Sequences for d4g7gc_:

Sequence; same for both SEQRES and ATOM records:

>d4g7gc_ a.104.1.0 (C:) automated matches {Trypanosome (Trypanosoma brucei) [TaxId: 5691]}
gklppvypvtvpilghiiqfgksplgfmqeckrqlksgiftinivgkrvtivgdphehsr
fflprnevlsprevysfmvpvfgegvayaapyprmreqlnflaeeltiakfqnfvpaiqh
evrkfmaanwdkdegeinlledcstmiintacqclfgedlrkrldarrfaqllakmessl
ipaavflpillklplpqsarcheartelqkilseiiiarkeeevnkdsstsdllsgllsa
vyrdgtpmslhevcgmivaamfagqhtssitttwsmlhlmhpanvkhlealrkeieefpa
qlnynnvmdempfaercaresirrdppllmlmrkvmadvkvgsyvvpkgdiiacspllsh
hdeeafpeprrwdperdekvegafigfgagvhkcigqkfgllqvktilatafrsydfqll
rdevpdpdyhtmvvgptasqcrvkyirr

Timeline for d4g7gc_:

• d4g7gc_ first appeared in SCOPe 2.03
  
• d4g7gc_ appears in SCOPe 2.05
  
• d4g7gc_ appears in SCOPe 2.07
  
• d4g7gc_ appears in the current release, SCOPe 2.08