SCOPe 2.08: Domain d4g2ya1: 4g2y A:535-858

Lineage for d4g2ya1 (4g2y A:535-858)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein automated matches [190370] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187208] (27 PDB entries)

8. Domain d4g2ya1: 4g2y A:535-858 [221674]
   Other proteins in same PDB: d4g2ya2
   automated match to d3siea_
   complexed with mg, ni5, peg, zn

Details for d4g2ya1

PDB Entry: 4g2y, 2.4 Å

PDB Description: Crystal structure of PDE5A complexed with its inhibitor

PDB Compounds: (A:) cGMP-specific 3',5'-cyclic phosphodiesterase

SCOPe Domain Sequences for d4g2ya1:

Sequence, based on SEQRES records:

>d4g2ya1 a.211.1.2 (A:535-858) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhev
lcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshd
ldhrgvnnsyiqrsehplaqlychsimehhhfdqclmilnspgnqilsglsieeykttlk
iikqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpi
qqriaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyealth
vsedcfplldgcrknrqkwqalae

Sequence, based on observed residues (ATOM records):

>d4g2ya1 a.211.1.2 (A:535-858) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhev
lcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalshd
ldhrgvnnsplaqlychsimehhhfdqclmilnspgnqilsglsieeykttlkiikqail
atdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpwpiqqriael
vateffdknkipsmqvgfidaiclqlyealthvsedcfplldgcrknrqkwqalae

Timeline for d4g2ya1:

• d4g2ya1 first appeared in SCOPe 2.03, called d4g2ya_
  
• d4g2ya1 appears in SCOPe 2.07