SCOPe 2.07: Domain d4g1fd1: 4g1f D:41-508

Lineage for d4g1fd1 (4g1f D:41-508)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.70: 8-bladed beta-propeller [50997] (3 superfamilies)
   consists of eight 4-stranded beta-sheet motifs; meander
   also found in some members of the WD40-repeat superfamily

4. Superfamily b.70.3: DPP6 N-terminal domain-like [82171] (1 family)
   automatically mapped to Pfam PF00930

5. Family b.70.3.1: DPP6 N-terminal domain-like [82172] (3 proteins)
   Pfam PF00930

6. Protein Dipeptidyl peptidase IV/CD26, N-terminal domain [82173] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [82174] (98 PDB entries)
   Uniprot P27487 39-776 ! Uniprot P27487 ! Uniprot P27487

8. Domain d4g1fd1: 4g1f D:41-508 [221656]
   Other proteins in same PDB: d4g1fa2, d4g1fb2, d4g1fb3, d4g1fc2, d4g1fd2
   automated match to d1orva1
   complexed with 0wg, nag

Details for d4g1fd1

PDB Entry: 4g1f, 2.9 Å

PDB Description: crystal structure of human dipeptidyl peptidase iv in complex with a pyridopyrimidinedione analogue

PDB Compounds: (D:) dipeptidyl peptidase 4

SCOPe Domain Sequences for d4g1fd1:

Sequence, based on SEQRES records:

>d4g1fd1 b.70.3.1 (D:41-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
ktytltdylkntyrlklyslrwisdheylykqennilvfnaeygnssvflenstfdefgh
sindysispdgqfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwspv
ghklayvwnndiyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspng
tflayaqfndtevplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssvt
natsiqitapasmligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwncl
varqhiemsttgwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitkg
twevigiealtsdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysvs
fskeakyyqlrcsgpglplytlhssvndkglrvlednsaldkmlqnvq

Sequence, based on observed residues (ATOM records):

>d4g1fd1 b.70.3.1 (D:41-508) Dipeptidyl peptidase IV/CD26, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
ktytltdylkntyrlklyslrwisdheylykqnilvfnanssvfdefghsindysispdg
qfilleynyvkqwrhsytasydiydlnkrqliteeripnntqwvtwspvghklayvwnnd
iyvkiepnlpsyritwtgkediiyngitdwvyeeevfsaysalwwspngtflayaqfndt
evplieysfysdeslqypktvrvpypkagavnptvkffvvntdslssvtnatsiqitapa
smligdhylcdvtwatqerislqwlrriqnysvmdicdydessgrwnclvarqhiemstt
gwvgrfrpsephftldgnsfykiisneegyrhicyfqidkkdctfitkgtwevigiealt
sdylyyisneykgmpggrnlykiqlsdytkvtclscelnpercqyysvsfskeakyyqlr
csgpglplytlhssvndkglrvlednsaldkmlqnvq

Timeline for d4g1fd1:

• d4g1fd1 first appeared in SCOPe 2.03
  
• d4g1fd1 appears in SCOPe 2.06
  
• d4g1fd1 appears in the current release, SCOPe 2.08