SCOPe 2.08: Domain d4fv5a_: 4fv5 A:

Lineage for d4fv5a_ (4fv5 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4fv5a_: 4fv5 A: [221550]
   automated match to d3sa0a_
   complexed with edo, ek9, so4

Details for d4fv5a_

PDB Entry: 4fv5, 2.4 Å

PDB Description: Crystal Structure of the ERK2 complexed with EK9

PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d4fv5a_:

Sequence, based on SEQRES records:

>d4fv5a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyv
atrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsps
qedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqal
ahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpg

Sequence, based on observed residues (ATOM records):

>d4fv5a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvaatrwyrapeimlnt
ksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnylls
lphknkvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiae
apfkfdmelddlpkeklkelifeetarfqpg

Timeline for d4fv5a_:

• d4fv5a_ first appeared in SCOPe 2.03
  
• d4fv5a_ appears in SCOPe 2.07