SCOPe 2.07: Domain d4foab_: 4foa B:

Lineage for d4foab_ (4foa B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
   contains large mixed beta-sheet

4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families)
   automatically mapped to Pfam PF00303

5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)

6. Protein automated matches [190469] (17 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:1773] [189990] (2 PDB entries)

8. Domain d4foab_: 4foa B: [221389]
   Other proteins in same PDB: d4foaa2
   automated match to d3qj7c_
   complexed with ufp

Details for d4foab_

PDB Entry: 4foa, 2.25 Å

PDB Description: crystal structure of the mtb thya in complex with 5-fluoro-dump

PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d4foab_:

Sequence, based on SEQRES records:

>d4foab_ d.117.1.1 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
mtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayell
wflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllr
tdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnias
yallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsife
ytyedivvknydphpaikapv

Sequence, based on observed residues (ATOM records):

>d4foab_ d.117.1.1 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
mtpyedllrfvletgtpksdtgtrslfgqqmrydlsagfpllttkkvhfksvayellwfl
rgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllrtdp
dsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfniasyal
lthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsifeyty
edivvknydphpaikapv

Timeline for d4foab_:

• d4foab_ first appeared in SCOPe 2.03
  
• d4foab_ appears in SCOPe 2.06
  
• d4foab_ appears in the current release, SCOPe 2.08