Lineage for d4foab_ (4foa B:)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2972108Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. 2972109Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. 2972110Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)
  6. 2972567Protein automated matches [190469] (17 species)
    not a true protein
  7. 2972697Species Mycobacterium tuberculosis [TaxId:1773] [189990] (2 PDB entries)
  8. 2972699Domain d4foab_: 4foa B: [221389]
    Other proteins in same PDB: d4foaa2
    automated match to d3qj7c_
    complexed with ufp

Details for d4foab_

PDB Entry: 4foa (more details), 2.25 Å

PDB Description: crystal structure of the mtb thya in complex with 5-fluoro-dump
PDB Compounds: (B:) Thymidylate synthase

SCOPe Domain Sequences for d4foab_:

Sequence, based on SEQRES records: (download)

>d4foab_ d.117.1.1 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
mtpyedllrfvletgtpksdrtgtgtrslfgqqmrydlsagfpllttkkvhfksvayell
wflrgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllr
tdpdsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfnias
yallthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsife
ytyedivvknydphpaikapv

Sequence, based on observed residues (ATOM records): (download)

>d4foab_ d.117.1.1 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}
mtpyedllrfvletgtpksdtgtrslfgqqmrydlsagfpllttkkvhfksvayellwfl
rgdsnigwlhehgvtiwdewasdtgelgpiygvqwrswpapsgehidqisaaldllrtdp
dsrriivsawnvgeiermalppchaffqfyvadgrlscqlyqrsadlflgvpfniasyal
lthmmaaqaglsvgefiwtggdchiydnhveqvrlqlsreprpypkllladrdsifeyty
edivvknydphpaikapv

SCOPe Domain Coordinates for d4foab_:

Click to download the PDB-style file with coordinates for d4foab_.
(The format of our PDB-style files is described here.)

Timeline for d4foab_: