Lineage for d4fnxa_ (4fnx A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2222093Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2222094Protein automated matches [190417] (25 species)
    not a true protein
  7. 2222237Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)
  8. 2222288Domain d4fnxa_: 4fnx A: [221377]
    automated match to d2i0ya_
    complexed with gol

Details for d4fnxa_

PDB Entry: 4fnx (more details), 1.7 Å

PDB Description: Crystal structure of the apo R1275Q anaplastic lymphoma kinase catalytic domain
PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d4fnxa_:

Sequence, based on SEQRES records: (download)

>d4fnxa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnysfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvavktl
pevcseqdeldflmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretr
prpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfg
maqdiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympyps
ksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdv
intalpieygpl

Sequence, based on observed residues (ATOM records): (download)

>d4fnxa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
npnysfagktssisdlkevprknitlirglevyegqvspsplqvavktlpevcseqdeld
flmealiiskfnhqnivrcigvslqslprfillelmaggdlksflretrprpsqpsslam
ldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgmaqdiycamlp
vkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppk
ncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygpl

SCOPe Domain Coordinates for d4fnxa_:

Click to download the PDB-style file with coordinates for d4fnxa_.
(The format of our PDB-style files is described here.)

Timeline for d4fnxa_: