SCOPe 2.03: Domain d4fnwa_: 4fnw A:

Lineage for d4fnwa_ (4fnw A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d4fnwa_: 4fnw A: [221376]
   automated match to d2i0ya_
   complexed with gol

Details for d4fnwa_

PDB Entry: 4fnw, 1.75 Å

PDB Description: crystal structure of the apo f1174l anaplastic lymphoma kinase catalytic domain

PDB Compounds: (A:) ALK tyrosine kinase receptor

SCOPe Domain Sequences for d4fnwa_:

Sequence, based on SEQRES records:

>d4fnwa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rtstimtdynpnysfagktssisdlkevprknitlirglghgafgevyegqvsgmpndps
plqvavktlpevcseqdeldflmealiisklnhqnivrcigvslqslprfillelmaggd
lksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpg
rvakigdfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweif
slgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiileri
eyctqdpdvintalpieygplv

Sequence, based on observed residues (ATOM records):

>d4fnwa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rtstimtdynpnysfagktssisdlkevprknitlirglggevyegqvssplqvavktlp
evcseqdeldflmealiisklnhqnivrcigvslqslprfillelmaggdlksflretrp
rpsqpsslamldllhvardiacgcqyleenhfihrdiaarnclltcpgpgrvakigdfgm
ardiyrcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlef
vtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpiey
gplv

Timeline for d4fnwa_:

• d4fnwa_ is new in SCOPe 2.03-stable
  
• d4fnwa_ appears in SCOPe 2.04
  
• d4fnwa_ appears in the current release, SCOPe 2.08