Lineage for d4f6ha_ (4f6h A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1937671Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
    duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets
  4. 1937672Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (15 families) (S)
  5. 1937673Family d.157.1.1: Zn metallo-beta-lactamase [56282] (2 proteins)
  6. 1937674Protein Zn metallo-beta-lactamase [56283] (12 species)
  7. 1937758Species Pseudomonas aeruginosa, IMP-1 [TaxId:287] [56287] (7 PDB entries)
  8. 1937759Domain d4f6ha_: 4f6h A: [221053]
    automated match to d4f6za_
    complexed with po4, so4, zn

Details for d4f6ha_

PDB Entry: 4f6h (more details), 1.74 Å

PDB Description: mutagenesis of zinc ligand residue cys221 reveals plasticity in the imp-1 metallo-b-lactamase active site
PDB Compounds: (A:) Beta-lactamase

SCOPe Domain Sequences for d4f6ha_:

Sequence, based on SEQRES records: (download)

>d4f6ha_ d.157.1.1 (A:) Zn metallo-beta-lactamase {Pseudomonas aeruginosa, IMP-1 [TaxId: 287]}
lpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtwf
vergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvny
wlvknkievfypgpghtpdnvvvwlperkilfgggfikpyglgnlgdanieawpksakll
kskygkaklvvpshsevgdasllkltleqavkglneskkpskpsnwshpqfek

Sequence, based on observed residues (ATOM records): (download)

>d4f6ha_ d.157.1.1 (A:) Zn metallo-beta-lactamase {Pseudomonas aeruginosa, IMP-1 [TaxId: 287]}
lpdlkiekldegvyvhtsfeevngwgvvpkhglvvlvnaeaylidtpftakdteklvtwf
vergykikgsisshfhsdstggiewlnsrsiptyaseltnellkkdgkvqatnsfsgvny
wlvknkievfypgpghtpdnvvvwlperkilfgggfikpyglgnlgdanieawpksakll
kskygkaklvvpshsevgdasllkltleqavkglneshpqfek

SCOPe Domain Coordinates for d4f6ha_:

Click to download the PDB-style file with coordinates for d4f6ha_.
(The format of our PDB-style files is described here.)

Timeline for d4f6ha_: