SCOPe 2.08: Domain d4em7a_: 4em7 A:

Lineage for d4em7a_ (4em7 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.0: automated matches [227160] (1 protein)
   not a true family

6. Protein automated matches [226867] (22 species)
   not a true protein

7. Species Streptococcus pneumoniae [TaxId:760835] [226426] (7 PDB entries)

8. Domain d4em7a_: 4em7 A: [220646]
   automated match to d1aj6a_
   complexed with 0ra

Details for d4em7a_

PDB Entry: 4em7, 1.9 Å

PDB Description: Crystal structure of a topoisomerase ATP inhibitor

PDB Compounds: (A:) DNA topoisomerase IV, B subunit

SCOPe Domain Sequences for d4em7a_:

Sequence, based on SEQRES records:

>d4em7a_ d.122.1.0 (A:) automated matches {Streptococcus pneumoniae [TaxId: 760835]}
qvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgfgdridvtinkdgsltv
qdhgrgmptgmhamgiptveviftilhaggkfgqggyktsgglhgvgssvvnalsswlev
eitrdgavykqrfenggkpvttlkkigtalksktgtkvtfmpdatifsttdfkyntiser
lnesafllknvtlsltdkrtdeaiefhyen

Sequence, based on observed residues (ATOM records):

>d4em7a_ d.122.1.0 (A:) automated matches {Streptococcus pneumoniae [TaxId: 760835]}
qvlegldavrkrpgmyigstdgaglhhlvweivdnavdealsgfgdridvtinkdgsltv
qdhgrgmptgmhamgiptveviftilhavgssvvnalsswleveitrdgavykqrfengg
kpvttlkkigtalksktgtkvtfmpdatifsttdfkyntiserlnesafllknvtlsltd
krtdeaiefhyen

Timeline for d4em7a_:

• d4em7a_ first appeared in SCOPe 2.03
  
• d4em7a_ appears in SCOPe 2.07