SCOPe 2.07: Domain d4eada2: 4ead A:71-335

Lineage for d4eada2 (4ead A:71-335)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.27: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52417] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 5 strands, order 32145; Rossmann-like

4. Superfamily c.27.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52418] (2 families)
   automatically mapped to Pfam PF00591

5. Family c.27.1.1: Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain [52419] (4 proteins)

6. Protein Thymidine phosphorylase [52420] (2 species)

7. Species Escherichia coli [TaxId:562] [52421] (7 PDB entries)

8. Domain d4eada2: 4ead A:71-335 [220386]
   Other proteins in same PDB: d4eada1, d4eada3, d4eada4
   automated match to d2tpta2
   complexed with 0np, gol, so4

Details for d4eada2

PDB Entry: 4ead, 1.5 Å

PDB Description: Thymidine phosphorylase from E.coli with 3'-azido-2'-fluoro-dideoxyuridine

PDB Compounds: (A:) thymidine phosphorylase

SCOPe Domain Sequences for d4eada2:

Sequence; same for both SEQRES and ATOM records:

>d4eada2 c.27.1.1 (A:71-335) Thymidine phosphorylase {Escherichia coli [TaxId: 562]}
dwkslhlngpivdkhstggvgdvtslmlgpmvaacggyipmisgrglghtggtldklesi
pgfdifpddnrfreiikdvgvaiigqtsslapadkrfyatrditatvdsiplitasilak
klaegldalvmdvkvgsgafmptyelsealaeaivgvangagvrttalltdmnqvlassa
gnavevreavqfltgeyrnprlfdvtmalcvemlisgklakddaearaklqavldngkaa
evfgrmvaaqkgptdfvenyakylp

Timeline for d4eada2:

• d4eada2 first appeared in SCOPe 2.03
  
• d4eada2 appears in SCOPe 2.06
  
• d4eada2 appears in the current release, SCOPe 2.08