Lineage for d4e4la_ (4e4l A:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2586062Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2586063Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2591262Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2591263Protein automated matches [190417] (35 species)
    not a true protein
  7. 2591422Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)
  8. 2591573Domain d4e4la_: 4e4l A: [220300]
    automated match to d3bhhd_
    complexed with 0nh

Details for d4e4la_

PDB Entry: 4e4l (more details), 2 Å

PDB Description: JAK1 kinase (JH1 domain) in complex with compound 30
PDB Compounds: (A:) Tyrosine-protein kinase JAK1

SCOPe Domain Sequences for d4e4la_:

Sequence, based on SEQRES records: (download)

>d4e4la_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadlkk
eieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlkya
vqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdsp
vfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrl
vntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

Sequence, based on observed residues (ATOM records): (download)

>d4e4la_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkhiadlkkeieilr
nlyhenivkykgictgiklimeflpsgslkeylpknknkinlkqqlkyavqickgmdylg
srqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwyapeclmq
skfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntlkegkrlp
cppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

SCOPe Domain Coordinates for d4e4la_:

Click to download the PDB-style file with coordinates for d4e4la_.
(The format of our PDB-style files is described here.)

Timeline for d4e4la_: