Lineage for d4e41g2 (4e41 G:93-190)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2020524Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 protein domains)
  6. 2022117Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)
  7. 2022125Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (40 PDB entries)
    Uniprot P04229 30-219
    probably orthologous to the mouse I-E group
  8. 2022151Domain d4e41g2: 4e41 G:93-190 [220259]
    Other proteins in same PDB: d4e41a1, d4e41a2, d4e41b1, d4e41d1, d4e41d2, d4e41e1, d4e41e2, d4e41f1, d4e41f2, d4e41g1, d4e41i1, d4e41i2, d4e41j1, d4e41j2
    automated match to d1klub1
    complexed with na; mutant

Details for d4e41g2

PDB Entry: 4e41 (more details), 2.6 Å

PDB Description: Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
PDB Compounds: (G:) HLA class II histocompatibility antigen, DRB1-1 beta chain

SCOPe Domain Sequences for d4e41g2:

Sequence, based on SEQRES records: (download)

>d4e41g2 b.1.1.2 (G:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4e41g2 b.1.1.2 (G:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}

SCOPe Domain Coordinates for d4e41g2:

Click to download the PDB-style file with coordinates for d4e41g2.
(The format of our PDB-style files is described here.)

Timeline for d4e41g2: