Lineage for d4dw2u_ (4dw2 U:)

  1. Root: SCOPe 2.04
  2. 1510239Class b: All beta proteins [48724] (176 folds)
  3. 1545310Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 1545311Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 1545555Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)
  6. 1547005Protein Urokinase-type plasminogen activator (LMW U-PA), catalytic domain [50586] (1 species)
  7. 1547006Species Human (Homo sapiens) [TaxId:9606] [50587] (68 PDB entries)
    Uniprot P00749 156-178,179-424
  8. 1547075Domain d4dw2u_: 4dw2 U: [220057]
    Other proteins in same PDB: d4dw2l1, d4dw2l2
    automated match to d4fuba_
    complexed with so4

Details for d4dw2u_

PDB Entry: 4dw2 (more details), 2.97 Å

PDB Description: The crystal structure of uPA in complex with the Fab fragment of mAb-112
PDB Compounds: (U:) urokinase-type plasminogen activator

SCOPe Domain Sequences for d4dw2u_:

Sequence, based on SEQRES records: (download)

>d4dw2u_ b.47.1.2 (U:) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
fttienqpwfaaiyrrhrggsvtyvcggslispcwvisathcfidypkkedyivylgrsr
lnsntqgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqtialpsm
yndpqfgtsceitgfgkeqstdylypeqlkmtvvklishrecqqphyygsevttkmlcaa
dpqwktdscqgdsggplvcslqgrmtltgivswgrgcalkdkpgvytrvshflpwirsht
k

Sequence, based on observed residues (ATOM records): (download)

>d4dw2u_ b.47.1.2 (U:) Urokinase-type plasminogen activator (LMW U-PA), catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
fttienqpwfaaiyrrvtyvcggslispcwvisathcfidypkkedyivylgrsrlnsnt
qgemkfevenlilhkdysadtlahhndiallkirskegrcaqpsrtiqtialpsmyndpq
fgtsceitgfgkeqstdylypeqlkmtvvklishrecyygsevttkmlcaadpqwqgdsg
gplvcslqgrmtltgivswgrkpgvytrvshflpwirshtk

SCOPe Domain Coordinates for d4dw2u_:

Click to download the PDB-style file with coordinates for d4dw2u_.
(The format of our PDB-style files is described here.)

Timeline for d4dw2u_: