SCOPe 2.08: Domain d1a22b1: 1a22 B:233-328

Lineage for d1a22b1 (1a22 B:233-328)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.2: Fibronectin type III [49265] (2 families)

5. Family b.1.2.1: Fibronectin type III [49266] (45 proteins)
   Pfam PF00041

6. Protein Growth hormone receptor [49280] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49281] (6 PDB entries)
   tandem of fibronectin type III domains

8. Domain d1a22b1: 1a22 B:233-328 [22003]
   Other proteins in same PDB: d1a22a_

Details for d1a22b1

PDB Entry: 1a22, 2.6 Å

PDB Description: human growth hormone bound to single receptor

PDB Compounds: (B:) growth hormone receptor

SCOPe Domain Sequences for d1a22b1:

Sequence, based on SEQRES records:

>d1a22b1 b.1.2.1 (B:233-328) Growth hormone receptor {Human (Homo sapiens) [TaxId: 9606]}
pkftkcrsperetfschwtdevhhgtknlgpiqlfytrrntqewtqewkecpdyvsagen
scyfnssftsiwipycikltsnggtvdekcfsvdei

Sequence, based on observed residues (ATOM records):

>d1a22b1 b.1.2.1 (B:233-328) Growth hormone receptor {Human (Homo sapiens) [TaxId: 9606]}
pkftkcrsperetfschwtlgpiqlfytrrntqewtqewkecpdyvsagenscyfnssft
siwipycikltsnggtvdekcfsvdei

Timeline for d1a22b1:

• d1a22b1 first appeared (with stable ids) in SCOP 1.55
  
• d1a22b1 appears in SCOPe 2.07