Lineage for d4drib1 (4dri B:2025-2112)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2311272Fold a.24: Four-helical up-and-down bundle [47161] (28 superfamilies)
    core: 4 helices; bundle, closed or partly opened, left-handed twist; up-and-down
  4. 2311691Superfamily a.24.7: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47212] (1 family) (S)
    automatically mapped to Pfam PF08771
  5. 2311692Family a.24.7.1: FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) [47213] (2 protein domains)
  6. 2311693Protein mTOR FKBP12–rapamycin-binding (FRB) domain [47214] (1 species)
  7. 2311694Species Human (Homo sapiens) [TaxId:9606] [47215] (11 PDB entries)
  8. 2311695Domain d4drib1: 4dri B:2025-2112 [219969]
    Other proteins in same PDB: d4dria_, d4drib2
    automated match to d4drhe_
    complexed with rap

Details for d4drib1

PDB Entry: 4dri (more details), 1.45 Å

PDB Description: Co-crystal structure of the PPIase domain of FKBP51, Rapamycin and the FRB fragment of mTOR
PDB Compounds: (B:) Serine/threonine-protein kinase mTOR

SCOPe Domain Sequences for d4drib1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4drib1 a.24.7.1 (B:2025-2112) mTOR FKBP12–rapamycin-binding (FRB) domain {Human (Homo sapiens) [TaxId: 9606]}
emwhegleeasrlyfgernvkgmfevleplhammergpqtlketsfnqaygrdlmeaqew
crkymksgnvkdltqawdlyyhvfrris

SCOPe Domain Coordinates for d4drib1:

Click to download the PDB-style file with coordinates for d4drib1.
(The format of our PDB-style files is described here.)

Timeline for d4drib1:

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Domains from same chain:
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d4drib2
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Domains from other chains:
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d4dria_