SCOPe 2.03: Domain d4df4a2: 4df4 A:423-832

Lineage for d4df4a2 (4df4 A:423-832)

1. Root: SCOPe 2.03

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.1: DNA polymerase I [56673] (5 proteins)

6. Protein DNA polymerase I (Klenow fragment) [56674] (3 species)

7. Species Thermus aquaticus [TaxId:271] [56676] (24 PDB entries)

8. Domain d4df4a2: 4df4 A:423-832 [219734]
   Other proteins in same PDB: d4df4a1
   automated match to d1jxea2
   protein/DNA complex; complexed with 0l3, edo, mg

Details for d4df4a2

PDB Entry: 4df4, 2.2 Å

PDB Description: Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 7-(N-(10-hydroxydecanoyl)-aminopentinyl)-7-deaza-2 -dATP

PDB Compounds: (A:) DNA polymerase I, thermostable

SCOPe Domain Sequences for d4df4a2:

Sequence; same for both SEQRES and ATOM records:

>d4df4a2 e.8.1.1 (A:423-832) DNA polymerase I (Klenow fragment) {Thermus aquaticus [TaxId: 271]}
eerllwlyreverplsavlahmeatgvrldvaylralslevaeeiarleaevfrlaghpf
nlnsrdqlervlfdelglpaigktektgkrstsaavlealreahpivekilqyreltklk
styidplpdlihprtgrlhtrfnqtatatgrlsssdpnlqnipvrtplgqrirrafiaee
gwllvaldysqielrvlahlsgdenlirvfqegrdihtetaswmfgvpreavdplmrraa
ktinfgvlygmsahrlsqelaipyeeaqafieryfqsfpkvrawiektleegrrrgyvet
lfgrrryvpdlearvksvreaaermafnmpvqgtaadlmklamvklfprleemgarmllq
vhdelvleapkeraeavarlakevmegvyplavplevevgigedwlsake

Timeline for d4df4a2:

• d4df4a2 is new in SCOPe 2.03-stable
  
• d4df4a2 appears in SCOPe 2.04
  
• d4df4a2 appears in the current release, SCOPe 2.08